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S. Ji, S. Park, J. Choo, and H. R. Koh, "Sensitive Gene Detection by Visualizing Cas12a-Mediated Trans-Cleavage of Quenched Hairpin DNA Probes", (in preparation) (2025)
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H. R. Koh*, J. Jung, Y. H. Park, and S. K. Kim*, "Stepwise Kinetics of a DNA Enzyme Reaction via Single-Molecule Analysis", (under revision) (2025)
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S. Kim, W.-J. Lee, H. K. Lee, S. Ji, J. K. Hur*, S. H. Lee*, and H. R. Koh*, "Ultrasensitive single-point mutation detection via digital counting of individual dCas9-DNA complexes", Sens. Actuator B Chem. 444, 138466 (2025)
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S. Ji, E. Cho, H. Park, H. Shin, and H. R. Koh, "Quantification of metal ions through metal ion-induced folding of hairpin DNA using single-molecule FRET", Anal. Chim. Acta 1370, 344387 (2025)
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J. Park, Y.-J. Jeong, K. Chauhan, H. R. Koh, and D.-E. Kim, "ATPase-dependent duplex nucleic acid unwinding by SARS-CoV-2 nsP13 relies on facile binding and translocation along single-stranded nucleic acid", J. Biol. Chem. 301, 110373 (2025)
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E. Cho, S. Ji, J. Moon and H. R. Koh, "Fluorescence imaging of microplastics and nanoplastics in biological samples", Mol. Cell. Toxicol. (2025)
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S.-Y. Chun, C. Park, J. Oh, H.-J. Yoon, T.-I. Kim, Y. Kim, S. W. Ham, H. R. Koh, H. H. Lee, H. Y. Kim, and K. Oh, "Thio)chromenone derivatives exhibit anti-metastatic effects through selective inhibition of uPAR in cancer cell lines: discovery of an uPAR-targeting fluorescent probe", Chem. Commun. 61, 909 (2025)
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G. B. Song, J. Nam, S. Ji, G. Woo, S. Park, B. Kim, J. Hong, M. G. Choi, S. Kim, C. Lee, W. Lim, S. Yoon, J.-M. Kim, W. J. Choi, M. J. Choi, H. R. Koh, T.-G. Lim and S. Hong, “Deciphering the links: Fragmented polystyrene as a driver of skin inflammation”, J. Haz. Mat. 480, 135815 (2024)
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J. Oh, H. Jang, H. R. Koh* and S. W. Ham*, “Transport Mechanism for Nuclear Localization of Irradiation-Activated EGFR Measured by Single-Molecule Pull-Down Assay”, Biochemistry 62, 971 (2023)
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K. Y. Baek, S. Kim and H. R. Koh, “Molecular Tension Probes to Quantify Cell-Generated Mechanical Forces”, Mol. Cells 45, 26 (2022)
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S. Ji, S. Kim, H. Kim and H. R. Koh, “Investigation on photobleaching of fluorophores: Effect of excitation power and buffer system”, Bull. Korean Chem. Soc. 43, 191 (2022)
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S. Kim*, S. Ji* and H. R. Koh, “CRISPR as a Diagnostic Tool”, Biomolecules 11, 1162 (2021) /*co-first author/
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C. Park, J. Oh, W. M. Lee, H. R. Koh, U. D. Sohn, S. W. Ham and K. Oh, “Inhibition of NUPR1-Karyopherin β1 Binding Increases Anticancer Drug Sensitivity”, Int. J. Mol. Sci. 22, 2794 (2021)
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Y. Lim, S. Kim, S. Kim, D.-I. Kim, K. W. Kang, S.-H. Hong, S.-M. Lee, H. R. Koh* and Y.-J. Seo*, “n-3 Polyunsaturated Fatty Acids Impede the TCR Mobility and the TCR–pMHC Interaction of Anti-Viral CD8+ T Cells”, Viruses 12, 639 (2020)
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J.-H. Kim, H. Lee, S. Song, H. R. Koh* and J. Sung*, “Observation time dependent mean first passage time of diffusion and subdiffusion processes”, J. Stat. Mech.: Theory Exp, 033204 (2020)
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A. G. Niaki, J. Sakar, X. Cai, K. Rhine, V. Vidaurre, B. Guy, M. Hurst, J. C. Lee, H. R. Koh, L. Guo, C. M. Fare, J. Shorter and S.Myong, “Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS”, Mol. Cell 77, 82-94 (2020)
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J. Park, K. Sung, S. Y. Bak, H. R. Koh* and S. K. Kim*, “Positive Identification of DNA Cleavage by CRISPR-Cas9 Using Pyrene Excimer Fluorescence to Detect a Subnanometer Structural Change”, J. Phys. Chem. Lett. 10, 6208-6212 (2019)
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D. S. Lim, Y. J. Lee, J. H. Yoo, M. G. Choi, K. Paek, H. R. Koh* and S.-K. Chang*, “Fluorometric analysis of peracetic acid by the oxidative hydroxylation of a phenylboronic acid containing dye”, Sens. Actuator B Chem. 298, 126824 (2019)
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H. R. Koh and S.Myong, “Single-Cell Imaging Approaches for Studying Small-RNA-Induced Gene Regulation”, Biophys J. 115, 203-208 (2018)
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H. R. Koh, R. Roy, M. Sorokina, G. Q. Tang, D. Nandakuma, S. S. Patel and T. Ha, “Correlating transcription initiation and conformational changes by a single subunit RNA polymerase with near base pair resolution”, Mol. Cell 70, 695-706 (2018)
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Y. Qiu, , S. Myong "Probing Dynamic Assembly and Disassembly of Rad51 Tuned by Srs2 Using smFRET”, Methods Enzymol. 600, 321-345 (2018)
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H. R. Koh, A. Ghanbariniaki, and S. Myong, “RNA Stem Structure Governs Coupling of Dicing and Gene Silencing in RNA interference”, Proc. Nat’l Acad. Sci. U.S.A. 114, E10349-E10358 (2017)
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S. J. Park, S. Song, I. Jeong, H. R. Koh, J. Kim, and J. Sung, “Nonclassical Kinetics of Clonal yet Heterogeneous Enzymes”, J. Phys. Chem. Lett. 8, 3152-3158 (2017)
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H. R. Koh, M. A. Kidwell, J. A. Doudna and S. Myong, “RNA Scanning of a Molecular Machine with a Built-in Ruler”, J. Am. Chem. Soc. 139, 262-268 (2017)
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H. R. Koh, X. Wang and S. Myong, “Visualizing repetitive diffusion activity of double-strand RNA binding proteins by single molecule fluorescence assays”, Methods (2016)
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X. Wang, L. Vukovic, H. R. Koh, K. Schulten and S. Myong, “Dynamic profiling of double-stranded RNA binding proteins”, Nucleic Acids Res. 43, 7566-7576 (2015)
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H. R. Koh, L. Xing, L. Kleiman and S. Myong, “Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing”, Nucleic Acids Res. 42, 8556-8564 (2014)
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L. Vukovic, H. R. Koh, S. Myong and K. Schulten, “Substrate recognition and specificity of double-stranded RNA binding proteins”, Biochemistry 53, 3457-3466 (2014)
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Y. Qiu, E. Antony, S. Doganay, H. R. Koh, T. M. Lohman and S. Myong, “Srs2 prevents Rad51 filament formation by repetitive scrunching of DNA”, Nat. Commun. 4, 1-10 (2013)
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H. R. Koh, M. A. Kidwell, K. Ragunathan, J. A. Doudna and S. Myong, “ATP-independent diffusion of double-stranded RNA binding proteins”, Proc. Nat’l Acad. Sci. U.S.A. 110, 151-156 (2013)
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J. Jung, K.Y. Han, H. R. Koh, J. Lee, Y. M. Choi, C. Kim and S. K. Kim, “Effect of single-base mutation on activity and folding of 10-23 deoxyribozyme studied by three-color single-molecule ALEX FRET”, J. Phys. Chem. B. 116, 3007-3012 (2012)
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H. R. Koh, K. Y. Han, J. Jung and S. K. Kim, “Quantitative genotyping of single nucleotide polymorphism by single-molecule multi-color fluorescence resonance energy transfer”, Chem. Commun. 47, 10362-10364 (2011)
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N. K. Lee*, H. R. Koh*, K. Y. Han and S. K. Kim, “Single-molecule, real-time measurement of enzyme kinetics by alternating-laser excitation fluorescence resonance energy transfer”, Chem. Commun. 46, 4683-4685 (2010) /*co-first author/
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M. Sorokina, H. R. Koh, S. S. Patel and T. Ha, “ Fluorescent lifetime trajectories of a single fluorophore reveal reaction intermediates during transcription”, J. Am. Chem. Soc. 131, 9630-9631 (2009)
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N. K. Lee, H. R. Koh, K. Y. Han and S. K. Kim, “Folding of 8-17 deoxyribozyme studied by three-color alternating-laser excitation of single-molecules”, J. Am. Chem. Soc. 129, 15526-15534 (2007)
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N. K. Lee, A.N. Kapanidis, H. R. Koh, Y. Wang, S. Ho, N. Gassman, S. Weiss and S. K. Kim, “Three-color alternating-laser excitation of single molecules : simultaneous monitoring of multiple interactions and distances”, Biophys. J. 92, 303-312 (2007)